The role of myocardial performance index and Nt-proBNP levels as a marker of heart dysfunction in nonalcoholic cirrhotic patients

Objective: Cardiac dysfunction has been reported in both cirrhotic and alcoholic patients. Our aim was to determine the relation of serum N-terminal pro-B-type natriuretic peptide (Nt-proBNP) levels myocardial performance index (MPI) disease severity nonalcoholic Patients Methods: In this prospective study including 25 patients 27 healthy controls, MPI assessed by pulsed-wave tissue Doppler imaging (PW-TDI). The determined Child–Turcotte–Pugh (CTP ) model for end-stage liver (MELD) scores. Results: There were no statistically significant differences between controls (p< 0.246). Nt-proBNP 0.0003), cardiac output (CO) 0.0002), left ventricular end-systolic (LVES) volume 0.031) QT interval 0.0001) increased. Left systolic function normal all when compared controls. positively correlated with MELD scores 0.0001, r= 0.59), duration CO (p= 0,001, 0.44), right atrial (RA) area 0.026, 0.31) negatively diastolic BP 0.015, -0.34). Conclusion: We conclude that patients, normal. hyperdynamic circulation.